EGGERT Engineering
Production of dry microbial biomass and pharmaceuticals by Prombiopharm JSC
Gmp-certified clean rooms
Moscow Region
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Prombiopharm produces probiotics – innovative medical immunobiological drugs. These are based on lyophilised biomass of bifidobacteria.

Probiotics are used for treatment and prevention of gastrointestinal diseases in humans and animals, and for production of medicines and functional foods. In addition, the company carries out research and development work in cooperation with healthcare organisations.

Our task was to develop the working documentation for expanding the existing production capacity. We were responsible for the technological part of the construction project. The production facility is fully GMP-certified.
Vladimir Danilov
Director of Engineering
Any pharmaceutical production facility is a rather complex and painstaking task for the engineers. Many interrelated parameters, the requirements of production technologists and the GMP standards have to be considered.

At this site, the design was complicated by the conditions of reconstruction of the building. Space planning was not just dictated by technological considerations, but also by the layout of the solid walls.

In addition, the production of bacterial mass differs from other pharmaceutical plants in that we cannot disinfect the environment using conventional methods.

Disinfectants and ultraviolet light will kill not only foreign bacteria, but also the bacteria we need. The process must be carefully planned and additional measures must be taken to ensure that no micro-organisms can enter the production area during the product's processing.

In this case, a multi-stage sluice and step-by-step treatment system is used for everything that goes into production. All raw material and product movement must comply with the company's internal regulations. And most production processes are carried out automatically.
Project run by
Vladimir Danilov
Project lead
Alexander Dobryshin
Senior process engineer
Any questions? Please contact us. We shall be happy to advise you on all matters.
Express audit of the project documentation is free of charge.
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